Alyn H Morice Selected Research

Cough

1/2022	ATP, an attractive target for the treatment of refractory chronic cough.
1/2022	Efficacy and safety of gefapixant, a P2X3 receptor antagonist, in refractory chronic cough and unexplained chronic cough (COUGH-1 and COUGH-2): results from two double-blind, randomised, parallel-group, placebo-controlled, phase 3 trials.
1/2021	The Cough Reflex: The Janus of Respiratory Medicine.
10/2020	Azithromycin for sarcoidosis cough: an open-label exploratory clinical trial.
10/2020	Objective Assessment of Cough: An Early Marker of Response to Biological Therapies in Asthma?
10/2020	Rhinovirus-16 increases ATP release in A549 cells without concomitant increase in production.
1/2020	Gefapixant, a P2X3 receptor antagonist, for the treatment of refractory or unexplained chronic cough: a randomised, double-blind, controlled, parallel-group, phase 2b trial.
1/2020	ERS guidelines on the diagnosis and treatment of chronic cough in adults and children.
11/2019	Inhaled Corticosteroids and Placebo Treatment Effects in Adult Patients With Cough: A Systematic Review and Meta-analysis.
5/2019	N-Cinnamoylanthranilates as human TRPA1 modulators: Structure-activity relationships and channel binding sites.

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Alyn H Morice Research Topics

Disease

39	Cough 01/2022 - 10/2002
28	Chronic Cough 01/2022 - 10/2002
11	Asthma (Bronchial Asthma) 10/2020 - 09/2005
10	Chronic Obstructive Pulmonary Disease (COPD) 01/2018 - 11/2005
6	Cystic Fibrosis (Mucoviscidosis) 01/2017 - 01/2002
5	Hypersensitivity (Allergy) 10/2020 - 01/2010
5	Idiopathic Pulmonary Fibrosis 11/2018 - 04/2011
4	Pain (Aches) 05/2019 - 08/2014
4	Inflammation (Inflammations) 01/2017 - 07/2006
2	Cough-Variant Asthma 01/2020 - 09/2017
2	Dysgeusia (Parageusia) 01/2020 - 01/2019
2	Bronchitis 01/2020 - 09/2017
2	Pneumonia (Pneumonitis) 01/2018 - 01/2017
1	Infections 10/2020
1	Pulmonary Sarcoidosis 10/2020
1	Sarcoidosis (Schaumann Disease) 10/2020
1	Heart Failure 10/2019
1	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 04/2015
1	Neuroblastoma 08/2014
1	Hypothermia 02/2014
1	Pulmonary Hypertension 11/2013
1	Bronchogenic Carcinoma 01/2013
1	digital ulcers 01/2013
1	Neoplasms (Cancer) 11/2012
1	Dyspepsia (Indigestion) 07/2012
1	Heartburn (Pyrosis) 07/2012
1	Laryngeal Diseases 04/2011
1	cough hypersensitivity syndrome 04/2011
1	Rhinosinusitis 04/2011

Drug/Important Bio-Agent (IBA)

8	Adrenal Cortex Hormones (Corticosteroids)IBA 11/2019 - 03/2007
8	Citric Acid (Citrate)FDA LinkGeneric 09/2014 - 10/2002
7	Capsaicin (Zostrix)FDA Link 03/2017 - 10/2002
6	Purinergic P2X3 ReceptorsIBA 01/2022 - 09/2017
6	Antitussive Agents (Antitussives)FDA Link 01/2022 - 02/2007
6	Formoterol Fumarate (Oxis)FDA Link 01/2019 - 09/2005
5	GefapixantIBA 01/2022 - 01/2019
5	Pharmaceutical PreparationsIBA 01/2021 - 11/2009
4	AcidsIBA 01/2020 - 04/2011
4	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2018 - 08/2011
3	Adenosine Triphosphate (ATP)IBA 01/2022 - 01/2019
3	Azithromycin (Zithromax)FDA LinkGeneric 10/2020 - 12/2011
3	Morphine (MS Contin)FDA LinkGeneric 01/2020 - 02/2007
3	Fluticasone (Cutivate)FDA LinkGeneric 01/2018 - 07/2012
3	Dextromethorphan (Racemethorphan)FDA LinkGeneric 12/2014 - 05/2008
3	SteroidsIBA 11/2014 - 08/2010
3	Budesonide (Pulmicort)FDA LinkGeneric 07/2012 - 01/2008
2	SmokeIBA 01/2020 - 12/2009
2	AnkyrinsIBA 05/2019 - 06/2014
2	CationsIBA 05/2019 - 03/2012
2	Beclomethasone (Beclometasone)FDA Link 01/2019 - 10/2017
2	Histamine Antagonists (Antihistamines)IBA 09/2017 - 12/2008
2	ivacaftorIBA 01/2017 - 01/2016
2	Interleukin-8 (Interleukin 8)IBA 01/2017 - 07/2006
2	Opiate AlkaloidsIBA 09/2014 - 02/2007
2	AerosolsIBA 09/2014 - 01/2002
1	mepolizumabIBA 10/2020
1	MacrolidesIBA 10/2020
1	Anti-Bacterial Agents (Antibiotics)IBA 10/2020
1	Purinergic P2 Receptors (ADP Receptor)IBA 01/2020
1	Purinergic Receptors (Receptors, Purine)IBA 01/2020
1	Atrial Natriuretic Factor (ANF)IBA 10/2019
1	Brain Natriuretic Peptide (Natrecor)FDA Link 10/2019
1	TRPA1 Cation ChannelIBA 05/2019
1	N-acetyltryptophanamide (NATA)IBA 01/2019
1	Albuterol (Salbutamol)FDA LinkGeneric 01/2019
1	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 11/2018
1	SodiumIBA 10/2017
1	Opioid Analgesics (Opioids)IBA 09/2017
1	TheobromineIBA 07/2017
1	Aromatase (CYP19)IBA 12/2016
1	Aromatase InhibitorsIBA 12/2016
1	Androstenedione (4 Androstene 3,17 dione)IBA 12/2016
1	aclidinium bromideIBA 01/2016
1	butamirateIBA 12/2014
1	Codeine (Codeine Phosphate)FDA LinkGeneric 09/2014
1	DNA (Deoxyribonucleic Acid)IBA 08/2014
1	antibiotic G 418IBA 08/2014
1	src-Family KinasesIBA 08/2014
1	Potassium Chloride FDA LinkGeneric 02/2014
1	Biological ProductsIBA 01/2014
1	HydrogenIBA 11/2013
1	vilanterolIBA 07/2013
1	fluticasone furoate FDA Link 07/2013
1	Endothelin Receptor AntagonistsIBA 01/2013
1	N 30IBA 01/2013
1	Carcinoembryonic AntigenIBA 11/2012
1	Fluticasone-Salmeterol Drug Combination (Advair)FDA Link 07/2012
1	Protons (Proton)IBA 03/2012
1	Esomeprazole (Nexium)FDA Link 10/2011
1	Proton Pump InhibitorsIBA 10/2011

Therapy/Procedure

16	Therapeutics 01/2022 - 02/2007
3	Metered Dose Inhalers (Metered Dose Inhaler) 01/2008 - 09/2005
2	Drug Therapy (Chemotherapy) 01/2020 - 04/2013
2	Fundoplication 07/2012 - 01/2009
2	Radiation Dosimeters 08/2010 - 01/2005
1	Biological Therapy 10/2020
1	Palliative Care (Palliative Therapy) 09/2017
1	Radiotherapy 04/2015
1	Rewarming 02/2014
1	Aftercare (After-Treatment) 06/2012